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Torsade de pointes induced by short-term oral amiodarone therapy.
Authors:Hong Euy Lim  Hui-Nam Pak  Jeong Cheon Ahn  Woo Hyuk Song  Young-Hoon Kim
Affiliation:Division of Cardiology, Korea University Cardiovascular Center, Ansan Hospital, 516 Gojan-1-Dong, Danwon-ku, Ansan 425-707, Republic of Korea. hongeuy@korea.ac.kr
Abstract:
Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed during long-term drug administration, usually in conjunction with electrolyte disturbances, a change in drug dosage, or concomitant drug therapy. We report two cases of amiodarone-induced TdP shortly after administration of a low dose of oral amiodarone, in the absence of predisposing factors.
Keywords:Amiodarone   Torsade de pointes   QT prolongation
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