Heart resistance to oxidative stress in rats of different genetic strains |
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| Authors: | L.?M.?Belkina mailto:lmgb@yandex.ru" title=" lmgb@yandex.ru" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,V.?L.?Lakomkin,A.?G.?Zhukova,T.?N.?Kirillina,V.?A.?Saltykova,T.?G.?Sazontova,V.?I.?Kapel’ko |
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| Affiliation: | (1) Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow;(2) Russian Cardiology Research-and-Production Center, Russian Ministry of Health, Moscow |
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| Abstract: | ![]()
In August rats reperfusion after regional myocardial ischemiain situ or intracoronary administration of hydrogen peroxide less significantly suppressed contractile activity of the heart compared to Wistar rats. Activities of catalase and superoxide dismutase in the myocardium during reperfusion remained unchanged in August rats. In Wistar rats a profound inhibition of cardiac function was accompanied by a decrease in enzyme activity. Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 9, pp. 250–253, September, 2004 |
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| Keywords: | August and Wistar rats myocardial ischemia and reperfusion antioxidant enzymes hydrogen peroxide |
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