Preclinical efficacy of anecortave acetate |
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Authors: | Clark Abbot F |
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Affiliation: | Discovery Research, Alcon Research, Ltd. Ft. Worth, Texas 76134, USA. |
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Abstract: | Anecortave acetate is a unique ocular angiostatic cortisene that has broad-based anti-angiogenic activity in 14 different preclinical models of neovascularization, across multiple species and inducers of neovascularization. Anecortave acetate is being tested clinically for inhibition of choroidal neovascularization associated with age-related macular degeneration. |
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