3项检测对诊断儿童感染性疾病的意义与价值

目的：探讨C-反应蛋白（CRP）、白细胞（WBC）及异型淋巴细胞对诊断儿童感染性疾病的意义与价值。方法选择开封市第二人民医院儿科病房40例细菌性感染患者作为A组，病毒性感染40例患者作为B组，选择同期40例健康体检儿童作为C组，观察3组CRP、WBC及异型淋巴细胞情况。结果 A组患儿CRP、WBC明显高于B、C两组；CRP及WBC阳性检出率明显高于异型淋巴细胞的阳性率，差异均有统计学意义（P＜0．05）。B组异型细胞明显高于 A、C两组，异型淋巴细胞阳性检出率明显高于 CRP和 WBC ，差异均有统计学意义（ P＜0．05）。结论单纯WBC升高可能难以诊断儿童感染性疾病，结合CRP和异型淋巴细胞对于儿童感染性疾病的诊治具有一定指导意义，值得临床推荐使用。

Clinical value of C-reactive protein,white blood cell and atypical lymphocytes in diagnosis of children with infectious dis-eases

Objective To explore the clinical value of C-reactive protein（CRP） ,white blood cell（WBC） and a-typical lymphocytes in the diagnosis of pediatric infectious diseases .Methods Forty cases with bacterial infections were selected as group A ,40 cases with viral infection as group B ,40 healthy children in the same period as the group C ,then observed their CRP ,WBC ,and atypical lymphocytes situation .Results CRP ,WBC of children in group A were significant higher than the other two groups ;positive detection rate of CRP and WBC were significant higher than that of atypical lymphocytes （P〈0 .05） .Atypical cells of group B was significant higher than the other two groups（P〈0 .05） .Conclusion It is difficult to diagnose infectious diseases in children according to the pure elevated WBC .Is is important to combine the detection of CRP and atypical lymphocytes for the diagnosis and treatment of in-fectious diseases in children ,which is worth of generalizing .