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Acetylcholine receptor antibody in myasthenia gravis
Authors:P. E. Marchiori  M. dos  Reis  M. E. Quevedo  M. Scaff  W. Cossermelli  J. L. Assis  R. M. de  Oliveira
Affiliation:Department of Neurology, S?o Paulo University Medical School, Brazil.
Abstract:Radioimmunoassay techniques were used to detect antibodies to the acetylcholine receptor (AAChR) in 164 patients with adult-onset myasthenia gravis. AAChR levels above 0.6 nM/l were considered pathological and were found in 67% of the patients with an average value of 58.99 +/- 125.02 nM/l (0.6-900.0). Correlation, with clinical functional status, the histopathological thymus alterations and the different therapeutics used did not disclose any statistically significant differences.
Keywords:myasthenia gravis    acetylcholine receptor antibody
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