正交设计优选解酒肝康颗粒的提取工艺

目的对解酒肝康颗粒的提取工艺进行正交设计研究。方法以人参、丹参等醇提得膏率，山楂等水提得膏率，丹参酮ⅡA为指标，采用正交设计法对解酒肝康颗粒的提取工艺进行优选。结果人参、丹参等加10倍量70％乙醇，回流提取2次，每次2h。山楂、人参、丹参残渣等加10倍量水，煎煮2次，每次2h。结论优选的提取工艺设计合理，有效成分提取效率较高。

Optimization of Extracting Technology of Jiejiu Gankang Granules by Orthogonal Design

Objective To study the extraction process of Jiejiu Gankang granules by orthogonal test, Methods With the ethanol extraction rates of the medical materials like ginseng, radix salviae miltiorrhizae, the water extraction rates of the medical materials like hawthorn, and Tanshinone IIA as the parameters, the extract conditions of Jiejiu Gankang granules was optimized by orthogonal design. Results The optimal preparation process was as follows., the mixture of medical materials like ginseng and Sehisandra ehinensis was refluxed twice with total 10 times of 70% alcohol, 2.0 hours for each time, and then the mixture of medical materials like hawthorn extracted twice with total 10 times of boiling water, 2.0 hours for each time. Conclusion The optimal preparation process is reasonable and with high extraction rate of active components.