小剂量血管加压素在感染性休克中的应用进展

血管加压素应用于感染性休克可以改善组织灌注,稳定血流动力学.它的主要作用机制是在感染性休克状态下,血浆血管加压素水平的相对性缺乏与血管对血管加压素的敏感性增强.目前研究主张小剂量血管加压素与其他血管活性药物联合使用治疗感染性休克,由于缺乏临床多中心随机对照研究,血管加压素仍是感染性休克的二线升压药.

Application of low-dose vasopressin in the management of septic shock

A number of recent reports suggest that vasopressin may improve organ perfusion and contribute usefully to the cardiovascular management of septic shock. The rationale for the use of vasopressin is its relative deficiency of plasma levels and hypersensitivity to its vasopressor effects during septic shock. Although it is being used more frequently, there are no randomized clinical trials comparing vasopressin as a first-line vasopressor.