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人外周血树状突细胞在体外对LAK杀伤活性的影响
引用本文:杨宁 缪继武. 人外周血树状突细胞在体外对LAK杀伤活性的影响[J]. 现代免疫学, 1996, 16(3): 164-166
作者姓名:杨宁 缪继武
作者单位:南京铁道医学院组胚教研室
基金项目:江苏省科委和铁道部资助
摘    要:
本文采用三因素不同水平的析因设计,研究了人外周血树状突细胞在体外对LAK抗肿瘤作用的影响。结果显示,3种浓度的树状突细胞均能增强LAK的杀伤活性(P<0.001),以中等浓度的树状突细胞作用最为明显。加入IL-2后,树状突细胞对LAK抗肿瘤活性的增强程度进一步提高。

关 键 词:人外周血,树状突细胞,LAK细胞,IL-2

In Vitro Effect of Dendritic Cells in Human Peripheral Blood on the Tumoricidal Activities of LAK Cells
Yang Ning, Miao Jiwu, Yin Lanzhen, Zhang Jicai, Zha Baoxing, Xu Jiadi. In Vitro Effect of Dendritic Cells in Human Peripheral Blood on the Tumoricidal Activities of LAK Cells[J]. Current Immunology, 1996, 16(3): 164-166
Authors:Yang Ning   Miao Jiwu   Yin Lanzhen   Zhang Jicai   Zha Baoxing   Xu Jiadi
Abstract:
In vitro effect of dendritic cells(DCs) in human peripheral blood on the tumoricidal activities of LAK was studied using three factors experiment design of different levels. The results showed that all three doses of DCs could enhance the killing activity of LAK (P<0.001), especially the middle dose of DCs. The enhancement of LAK cell activities by DC was further elevated after adding IL-2.
Keywords:human peripheral blood   dendritic cell   LAK cell   IL-2.  
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