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Tibolone histology of the endometrium and breast endpoints study: design of the trial and endometrial histology at baseline in postmenopausal women
Authors:Archer David F,Hendrix Susan,Ferenczy Alex,Felix Juan,Gallagher J Chris,Rymer Janice,Skouby Sven O,den Hollander Wil,Stathopoulos Victoria,Helmond Frans A  THEBES Study Group
Affiliation:a Department of Obstetrics and Gynecology, Contraceptive Research and Development Program Clinical Research Center, Eastern Virginia Medical School, Norfolk, Virginia
b Wayne State University/Hutzel Women's Hospital, Detroit, Michigan
c McGill University and Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada
d Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California
e Bone Metabolism Section, Creighton University Medical Center, Omaha, Nebraska
f King's College School of Medicine at Guy's and St. Thomas' Hospitals, Division of Obstetrics and Gynaecology, London, United Kingdom
g Department of Obstetrics and Gynecology, Frederiksberg Hospital, Copenhagen, Denmark
h NV Organon, Oss, the Netherlands
i Organon International, Roseland, New Jersey
Abstract:
Keywords:Tibolone   hormone therapy   endometrial safety   endometrial histology   endometrial hyperplasia   endometrial cancer   breast tenderness   vaginal bleeding   estrogen   progestin
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