| 兔局灶脑缺血后脑片[Ca~(2 )]i的变化 |
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| 引用本文： | 赵卫国,孙青芳,张天锡,田恒力,张学新.兔局灶脑缺血后脑片[Ca~(2 )]i的变化[J].中华急诊医学杂志,1997(6). |
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| 作者姓名： | 赵卫国 孙青芳 张天锡 田恒力 张学新 |
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| 作者单位： | 上海第二医科大学瑞金医院神经外科!上海，200025(赵卫国，孙青芳，张天锡，田恒力)，河北医学院附属四院神经外科(张学新) |
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| 摘 要： | 目的：研究脑缺血后脑片Ca2＋]i变化。方法：采用新型Ca2＋荧光指示剂Fura－2双波长法测定兔大脑中动脉阻塞（MCAo）局灶脑缺血后脑片细胞内游离钙（Ca2＋]i）。结果：脑缺血后脑组织Ca2＋]i显著升高。结论：Ca2＋]i在脑缺血损害中起重要作用。
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| 关 键 词： | MCAo 脑片 [Ca~(2＋)]i |
THE CHANGE OF [Ca~(2 )]i AFTER MCAo ISCHEMA IN RABBIT |
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| Zhao Weiguo,Sun Qingfang,Zhang Tianxi,et al..THE CHANGE OF [Ca~(2 )]i AFTER MCAo ISCHEMA IN RABBIT[J].Chinese Journal of Emergency Medicine,1997(6). |
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| Authors: | Zhao Weiguo Sun Qingfang Zhang Tianxi |
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| Abstract: | Aim: To study the changes of Ca2 ]i on brain slice after MCAo ischemia. Methods: The Ca2 ]i level was determined by new type Ca2 indicator-Fura-2/AM with double-wave length. Results: The Ca2 ]i was significantly increased after focal cerebral ischemia. Conclusion: These results suggested that Ca2 ]i increase after cerebral ischemia, which plays an important role in the damage to the ischemic brain tissue. |
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| Keywords: | MCAo [Ca~(2 )]i Brain slice |
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