|
|||||
|
|
| 金钱草壳聚糖微球制备工艺研究 | |
| 引用本文： | 丁立新,李春英,王心合. 金钱草壳聚糖微球制备工艺研究[J]. 中国当代医药, 2010, 17(2): 47-48 |
| 作者姓名： | 丁立新 李春英 王心合 |
| 作者单位： | 佳木斯大学药学院,黑龙江佳木斯,154007 |
| 基金项目： | 佳木斯大学2009科学技术研究项目 |
| 摘 要： | 目的：对金钱草壳聚糖微球的制备工艺和包封率、粒径等特性进行初步研究。方法：以生物降解材料壳聚糖为载体，采用乳化一交联法制备金钱草壳聚糖微球，并采用正交试验优化制备工艺。结果：所制备的金钱草壳聚糖微球外观圆整，平均粒径为48．34μm，载药量为15．11％，包封率为59．55％。结论：所制备的金钱草壳聚糖微球重现性良好，载药量较高，制备工艺可行。 |
| 关 键 词： | 金钱草 壳聚糖 微球 |
Study on Lysimachia Christinae Hance Chitosan microspheres preparation technology |
|
| DING Lixin,LI Chunying,WANG Xinhe. Study on Lysimachia Christinae Hance Chitosan microspheres preparation technology[J]. http://www.botanicus.org/, 2010, 17(2): 47-48 | |
| Authors: | DING Lixin LI Chunying WANG Xinhe |
| Affiliation: | DING Lixin, LI Chunying, WA NG X inhe (The College of Pharmacy of Jiamusi University,Jiamusi 154007,China) |
| Abstract: | Objective： To study the preparation technique of Lysimachia Christinae Hance Chitosan microspheres （LCH- CS-MS） and their characteristics.Methods： LCH-CS-MS were prepared by using Chitosan as corematerial and emulsion chemical-erosslinkingmethods.Results： LCH-CS-MS was regular in morphology with the mean diameter of 48.34μm,The loading amount of LCH-CS-MS was 15.11% and encapsulation efficiency was 59.55%.Conclusion： The preparation technology for LCH-CS-MS is applicable. |
| Keywords: | Lysimachia Christinae Hance Chitosan Mierospheres |
| 本文献已被 维普 万方数据 等数据库收录！ | |