| 3D打印多孔β-磷酸三钙负载聚乳酸-羟基乙酸共聚物抗结核药物缓释微球复合材料：构建及细胞毒性评价 |
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| 引用本文： | 孟 磊,甄 平,梁晓燕. 3D打印多孔β-磷酸三钙负载聚乳酸-羟基乙酸共聚物抗结核药物缓释微球复合材料：构建及细胞毒性评价[J]. 中国组织工程研究, 2016, 20(25): 3750-3756. DOI: 10.3969/j.issn.2095-4344.2016.25.016 |
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| 作者姓名： | 孟 磊 甄 平 梁晓燕 |
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| 作者单位： | 甘肃中医药大学，甘肃省兰州市 730000；解放军兰州军区兰州总医院全军骨科中心，甘肃省兰州市 730050 |
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| 基金项目： | 国家自然科学基金(81371983) |
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| 摘 要： | ![]()
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| 关 键 词： | 生物材料 材料相容性 3D打印 β-磷酸三钙负载抗结核药物缓释微球复合材料 生物相容性 CCK-8法 成骨细胞 相对增殖率 细胞毒性分级 国家自然科学基金 |
| 收稿时间： | 2016-03-22 |
Three-dimensionally printed porous beta-tricalcium phosphate scaffold loading poly(lactic-co-glycolic acid)/anti-tuberculosis drug control-release microspheres:a cytotoxic evaluation |
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| Meng Lei,Zhen Ping,Liang Xiao-yan. Three-dimensionally printed porous beta-tricalcium phosphate scaffold loading poly(lactic-co-glycolic acid)/anti-tuberculosis drug control-release microspheres:a cytotoxic evaluation[J]. Chinese Journal of Tissue Engineering Research, 2016, 20(25): 3750-3756. DOI: 10.3969/j.issn.2095-4344.2016.25.016 |
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| Authors: | Meng Lei Zhen Ping Liang Xiao-yan |
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| Affiliation: | Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China; Military Orthopedics Center, Lanzhou General Hospital of Lanzhou Military Region of Chinese PLA, Lanzhou 730050, Gansu Province, China |
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| Abstract: | ![]()
BACKGROUND:So far there is a lack of reliable biomedical evidence about the effects of three-dimensionally (3D) printed porous β-tricalcium phosphate (β-TCP) scaffold loading poly(lactic-co-glycolic acid) (PLGA)/anti-tuberculosis drug control-release microspheres on the growth and proliferation of cells, especially osteoblasts. |
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| Keywords: | Calcium Phosphates Antitubercular Agents Tissue Engineering |
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