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| 男性型秃头患者头皮雌,雄激素受体的检测及头发移？… | |
| 引用本文： | 陈学杰 龙道畸. 男性型秃头患者头皮雌,雄激素受体的检测及头发移？…[J]. 中华整形外科杂志, 2000, 16(2): 105-107 |
| 作者姓名： | 陈学杰 龙道畸 |
| 作者单位： | 湖北医科大学附属第一医院整形外科(陈学杰!430060，龙道畴!430060，王松山!430060)，湖北省洪湖市妇幼保健院(苗万青) |
| 摘 要： | 目的 研究头皮局部性激素水平在男性型秃发发生机理中的作用。方法 自１９９６－１９９８年应用荧光素类固醇激素结合法，对８例男性型秃发患者的正常生发区和秃发区的雌，雄激素受体进行对比检测，同时对自体头发移植术后供，受区头皮再生检测。结果 秃发区头皮外毛根鞘，皮脂腺及毛乳头中的雄激素受体阳性细胞百分率明显高于正常生发区，秃发区外毛根鞘中雌激素受体阳性细胞百分率明显高于正常生发区，而毛乳头中则低于正常生发 |
| 关 键 词： | 男性型秃发 头皮 性激素受体 头发移植术 |
| 修稿时间： | 1998-05-18 |
Determination of scalp ER and AR of patients with male pattern baldness and the effects of hair transplantation on them |
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| CHEN Xuejie,LONG Daochou,WANG Songshan,et al.. Determination of scalp ER and AR of patients with male pattern baldness and the effects of hair transplantation on them[J]. Chinese journal of plastic surgery, 2000, 16(2): 105-107 | |
| Authors: | CHEN Xuejie LONG Daochou WANG Songshan et al. |
| Affiliation: | Department of Plastic Surgery, First Affiliated Hospital of Hubei Medical University, Wuhan 430060, PR China. |
| Abstract: | Objective To study the role of sex hormone receptor capacity of the scalp in male pattern baldness(MPB).Methods Estrogen receptor(ER) and androgen receptor(AR) assays were performed using fluorescent steroid hormone conjugate technique (FSHCT) in hairness and bald scalp in 8 patients with MPB.Changes of ER and AR capacity in recipient and donor sites of hair transplantation in MPB scalps were examined.Results The percentage of AR staining cells in the outer root sheath,sebaceous gland and bulb papilla of the lesional scalps was significantly higher than that of hairness scalps (P<0 01) .The percentage of ER positive cells in the outer root sheath of lesional scalps increased significantly (P<0 01) .Conclusion Changes of contents of sex hormone receptors(SHR) in some sensitive area of the scalp induce MPB. |
| Keywords: | Male pattern baldness Hair transplantation Sex hormone receptor |
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