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Rapid time‐resolved magnetic resonance angiography via a multiecho radial trajectory and GraDeS reconstruction
Authors:Gregory R. Lee  Nicole Seiberlich  Jeffrey L. Sunshine  Timothy J. Carroll  Mark A. Griswold
Affiliation:1. Department of Radiology, School of Medicine, Case Western Reserve University / University Hospitals of Cleveland, Cleveland, Ohio, USA;2. Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA;3. Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA;4. Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, USA
Abstract:Contrast‐enhanced magnetic resonance angiography is challenging due to the need for both high spatial and temporal resolution. A multishot trajectory composed of pseudo‐random rotations of a single multiecho radial readout was developed. The trajectory is designed to give incoherent aliasing artifacts and a relatively uniform distribution of projections over all time scales. A field map (computed from the same data set) is used to avoid signal dropout in regions of substantial field inhomogeneity. A compressed sensing reconstruction using the GraDeS algorithm was used. Whole brain angiograms were reconstructed at 1‐mm isotropic resolution and a 1.1‐s frame rate (corresponding to an acceleration factor > 100). The only parameter which must be chosen is the number of iterations of the GraDeS algorithm. A larger number of iterations improves the temporal behavior at cost of decreased image signal‐to‐noise ratio. The resulting images provide a good depiction of the cerebral vasculature and have excellent arterial/venous separation. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.
Keywords:4D contrast enhanced angiography  time‐resolved angiography  GraDeS  compressed sensing
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