| 胰腺癌干细胞研究进展 |
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| 引用本文： | 朱建伟,熊力,马望,樊青霞,张亚娜 综述 文宇,苗雄鹰 审校. 胰腺癌干细胞研究进展[J]. 中国普通外科杂志, 2015, 24(9): 1304-1309 |
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| 作者姓名： | 朱建伟 熊力 马望 樊青霞 张亚娜 综述 文宇 苗雄鹰 审校 |
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| 作者单位： | （1. 中南大学湘雅二医院 普通外科，湖南 长沙 410011；2. 郑州大学第一附属医院 肿瘤科，河南 郑州 450000） |
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| 基金项目： | 国家自然科学基金资助项目（81372628）。 |
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| 摘 要： | 胰腺癌干细胞（PCSC）在胰腺癌的发生、发展过程中起着重要作用，且与胰腺癌的耐药、转移机制关系密切。PCSC的表面标志物、分离、鉴定、信号通路、微环境、耐药、转移和靶向治疗等方面的研究，将为临床胰腺癌的治疗提供新的方向。
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| 关 键 词： | 胰腺肿瘤；肿瘤干细胞；综述文献 |
| 收稿时间： | 2015-05-14 |
| 修稿时间： | 2015-08-15 |
Research progress of pancreatic cancer stem cells |
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| ZHU Jianwei,XIONG Li,MA Wang,FAN Qingxi,ZHANG Yan,WEN Yu,MIAO Xiongying. Research progress of pancreatic cancer stem cells[J]. Chinese Journal of General Surgery, 2015, 24(9): 1304-1309 |
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| Authors: | ZHU Jianwei XIONG Li MA Wang FAN Qingxi ZHANG Yan WEN Yu MIAO Xiongying |
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| Affiliation: | (1. Department of General Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, China; 2. Department of Oncology, the First Affiliated Hospital, Zhengzhou University, Zhengzhou 450000, China) |
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| Abstract: | Pancreatic cancer stem cells (PCSCs) play an important role in the occurrence and development of pancreatic cancer, and are also closely related to the mechanisms for chemotherapy resistance and metastasis of pancreatic cancer. Investigations of PCSCs with regard to their surface markers, isolation, identification, signal pathways, microenvironment, drug resistance, metastasis and targeted therapy may provide a new prospect for the clinical treatment of pancreatic cancer. |
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| Keywords: | Pancreatic Neoplasms Neoplastic Stem Cells Review |
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