| 抗凝血生物材料的合成研究 Ⅴ．聚醚氨酯表面肝素化的新途径 |
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| 引用本文： | 屠湘同,胡昕,李香梅,吴飞舟,周亮,林思聪. 抗凝血生物材料的合成研究 Ⅴ．聚醚氨酯表面肝素化的新途径[J]. 医学教育探索, 1995, 0(2) |
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| 作者姓名： | 屠湘同 胡昕 李香梅 吴飞舟 周亮 林思聪 |
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| 作者单位： | 南京大学高分子科学与工程系 |
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| 摘 要： | 本文报道聚醚氨酯表面肝素化的新途径：用聚醚氨酯预聚体、对一氯甲基苯乙烯、甲基丙烯酸甲酯三元共聚的方法，在聚氨酯链上导入活性氯甲基，氯甲基经三乙胺季控化后以离子键将肝素固定在共聚物表面。抗凝血初步试验表明，该途径相当有效。
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| 关 键 词： | 抗凝血，嵌段聚醚氨酯，肝素化 |
Synthetic Studies on Blood Compatible Biomaterials V. A New Way for Surface Heparinization of Copolymer of Poly (ether urethane) |
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| Tu Xiangtong,Hu Xin,Li Xiangmei,Wu Feizhou,Zhou Liang,Lin Sicong. Synthetic Studies on Blood Compatible Biomaterials V. A New Way for Surface Heparinization of Copolymer of Poly (ether urethane)[J]. Researches in Medical Education, 1995, 0(2) |
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| Authors: | Tu Xiangtong Hu Xin Li Xiangmei Wu Feizhou Zhou Liang Lin Sicong |
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| Abstract: | A novel segmented polyurethane which was prepared from copolymerization of polyether-urethane,-chloromethylstyrene and methylmathacrylate has been heperinized on its surface. In this pecedure,triethylamine was first reacted with active chloromethyl group |
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| Keywords: | ntithrombogenicity Heparinization Segmented polyetherurethane |
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