鼻炎宁颗粒治疗急性鼻窦炎的临床研究

目的：评价鼻炎宁颗粒治疗成人急性鼻窦炎的疗效及安全性。方法：122例年龄在18～70岁之间诊断为急性鼻窦炎受试者病例,连续服用鼻炎宁颗粒（15g/次,2次/d）20d,进行多中心的开放式研究。分别在治疗前后对病例进行症状、体征的评估,并记录治疗期间发生的不良事件。结果：临床治愈率15.5%,好转为70.7%,总有效率86.2%（P〈0.05）。受试病例中无发生不良反应者。结论：鼻炎宁颗粒治疗急性鼻窦炎有良好的临床疗效及安全性。

The Clinical Research of Biyan Ning Granules in Treating Acute Sinusitis in Adult Patients

Objective： To evaluate the efficacy and safety of Biyan Ning Granules in treating acute sinusitis in adults. Methods： Totally 122 patients were enrolled into the study,aged from 18 to 70. The dosages of Biyan Ning Granules were 15 g twice daily,the duration of treatment was 20 days. Symptoms and physical signs were evaluated before and after treatment,AEs if any would be reported. Results： A clinical response of＂cure＂and ＂improved＂were 15. 5% and 70. 7% of patients respectively. No incidence of adverse events was reported. Conclusion： Biyan Ning Granules is effective for treatment of acute sinusitis.