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COX-2、p53在鼻咽癌中的表达及临床意义
引用本文:蔡晓,钟慧玲,甘青,王绍忠. COX-2、p53在鼻咽癌中的表达及临床意义[J]. 青海医学院学报, 2011, 32(3): 172-175
作者姓名:蔡晓  钟慧玲  甘青  王绍忠
作者单位:青海省人民医院耳鼻喉科
摘    要:
目的 检测COX-2、p53在鼻咽癌组织中的表达,分析它们之间的相关性及对鼻咽癌的诊断、治疗及预后判断的临床意义.方法 收集存档鼻咽癌蜡块49例,其中有颈淋巴结转移者35例;随机取同期鼻咽部慢性粘膜炎活检蜡块34例用于对照.用免疫组化方法检测组织中COX-2、p53蛋白表达情况,并分析它们之间的相关性.结果 1.COX...

关 键 词:鼻咽癌  COX-2  p53

EXPRESSION AND CLINICAL SIGNIFICANCE OF COX-2 AND P53 IN NASOPHARYNGEAL CARCINOMA
Cai Xiao,Zhong Huiling,Gan Qing,Wang Shaozhong. EXPRESSION AND CLINICAL SIGNIFICANCE OF COX-2 AND P53 IN NASOPHARYNGEAL CARCINOMA[J]. Journal of Qinghai Medical College, 2011, 32(3): 172-175
Authors:Cai Xiao  Zhong Huiling  Gan Qing  Wang Shaozhong
Affiliation:Cai Xiao,Zhong Huiling,Gan Qing,Wang Shaozhong(Department of Otorhinolaryngology,Qinghai provincial people's hospital)
Abstract:
Objective Investigate the expression of COX-2 and p53 in tissue of nasopharyngeal carcinoma(NPC) and chronicity blennymenitis of pars nasalis pharynges and analyze the correlation between them and the clinical significance concerning with diagnosis,treatment,and prognosis.Methods Collected 49 cases of paraffin blocked NPC specimen including 35 cases of cervical lymph node metastasis.34 cases of paraffin blocked chronicity blennymenitis of pars nasalis pharynges were randomly collected at the same period for...
Keywords:Nasopharyngeal carcinoma Cyclooxygenase-2 p53  
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