筛检大肠癌前病变的研究：（附7603例结果分析）

本研究对35岁以上正常人群进行普查筛检,以期发现早期大肠癌。7603例受检者中试纸法粪便隐血试验的阳性率为12.9％(986例),应用我院自制的羊抗人血红蛋白抗体进行免疫法复检的阳性率仅为1.4％(108例)。90例免疫法阳性者接受纤维结肠镜检查,发现大肠病变23例(0.3％)。本研究结果表明,进行大范围普查筛检,可以提高病变检出率,并能检出亚临床状态的大肠癌前病变,进行防治观察。本研究采用的筛检法简便易行,经济实效。

A Study on Sequential Screening'' of Pre-malignant Diseases of Colon.An Analysis of 7603 Cases

Sequential Screening' was used to investigate 7603 healthy adults for the detection of early cancer and premalignant diseases of colon. Of them 986 cases (12. 9%) were positive for fecal occult blood by routine test and 108 (1.4%) were positive by immune reaction test (with sheep anti-human hemoglobulin antibody developed in our hospital). Ninty of the 108 were examined by colonascopy and subclinical colonic diseases were detected in 23 (0.3%). Evidently, the Sequential Screening'is very promaing in mass screening, in terms of economy and efficiency in detect- ing subclical premalignant diseases.