Hemophagocytic syndrome and T-cell lymphoma after kidney transplantation: a case report |
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| Authors: | P Peeters J Sennesael H De Raeve M De Waele D Verbeelen |
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| Institution: | (1) Department of Nephrology, University Hospital, Free University Brussels (VUB), Laarbeeklaan 101, B-1090 Brussels, Belgium Fax: +32 2 477 60 53, BE;(2) Department of Pathology, University Hospital, Free University Brussels (VUB), Laarbeeklaan 101, B-1090 Brussels, Belgium, BE;(3) Department of Hematology, University Hospital, Free University Brussels (VUB), Laarbeeklaan 101, B-1090 Brussels, Belgium, BE |
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| Abstract: | Lymphoma in immunocompromised transplant patients is a feared cause of morbidity and mortality. Superimposed on the lymphoma
and the transplantation immunosuppression is a rare condition: hemophagocytic syndrome (HS). HS is characterized by fever,
hepatosplenomegaly and lymphadenopathy, skin rashes, jaundice, coagulopathy, and phagocytosis of blood elements with pancytopenia.
Here we describe a rare but fatal case of a kidney transplant patient who developed T-cell lymphoma and HS, without evidence
of EBV replication. A short review of the diagnosis, treatment, and prognosis of HS is given.
Received: 4 March 1997 Received after revision: 6 June 1997 Accepted: 30 June 1997 |
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| Keywords: | Hemophagocytic syndrome kidney transplantation T-cell lymphoma kidney transplantation Kidney transplantation T-cell lymphoma hemophagocytic syndrome |
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