心电图碎片状QRS波群与心血管事件发生的相关性研究

目的探讨心电图碎片状QRS复合波（fQRs）与心血管事件发生的相关性。方法随机抽取1000份我院心血管内科住院患者的12导联平静心电图，排除存在束支传导阻滞或起搏心律者，剩余939份心电图对应的939例患者为研究对象，按照心电图中是否存在fQRs波分成2组，研究两组患者在性别、年龄、心血管事件发生率等方面差异是否具有统计学意义。结果心电图出现fQRs波组患者冠心病、心肌缺血的总发生率为19．6％，心肌梗死总发生率为10．5％，左心室肥厚发生率为34．7％，相对正常者占35．2％；心电图无fORs波出现组患者冠心病、心肌缺血的总发生率为8．2％，心肌梗死发生率为6．5％，左心室肥厚发生率为12．9％，相对正常者占72．4％。经两样本x2检验，P〈0．01，两组心血管事件发生情况差异有统计学意义。结论心电图中出现fQRs波患者心血管事件的发生率较心电图无fQRs波改变者显著升高（P〈0．01）。碎片状QRS波群的出现能在一定程度上提示心血管事件的发生。

The corelation study of fragmented QRS and cardiovacular events

Objective To investigate the correlation between fragmented QRS complexes（fQRS） and cardiovasculer events. Methods Retrospective review was performed on ECGs of 1000 patients. 61 （6%） patients were excluded from our analysis because of various bundle-branch block or paced rhythm. The data for the final cohort of 939 patients were analyzed in this study. According to the appearance of the fQRS in electrocardiogram or not, the patients were divided into fQRS or non-fQRS group. The difference of sex, age and cardiovascular events between two groups were evaluated. Results The cohort with fQRS demonstrated a significantly higher cardiovas- cular events compared with the non-fQRS cohort （P〈0.01）. In the fQRS group, the incidence of angina was 18.5%, the incidence of LVH was 34.7%, the incidence of acute myocardial infarction （AMI） was 7.2%, the in- cidence of old myocardial infarction （OMI） was 3.3%, and 35.2% patients was relatively normal. In the non-fQRS group, the incidence of angina was 6.7%, the incidence of LVH was 12.9%, the incidence of AMI was 4.5%, the incidence of OMI was 2.0%, and 73.5% patients was relatively normal. Conclusion The cardiovascular events increase in patients with fQRS. The presence of fQRS may indicate the cardiovascular events at some extent.