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Comparison of whole liver and small region-of-interest measurements of MRI liver R2* in children with iron overload |
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| Authors: | M. Beth McCarville Claudia M. Hillenbrand Ralf B. Loeffler Matthew P. Smeltzer Ruitan Song Chin-Shang Li Jane S. Hankins |
| Affiliation: | (1) Department of Radiological Sciences, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Mail Stop 210, Memphis, TN 38105, USA;(2) Department of Radiology, The University of Tennessee College of Medicine, Memphis, TN, USA;(3) Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, TN, USA;(4) Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN, USA |
| Abstract: | BackgroundMeasurement of liver MRI T2* and R2* is emerging as a reliable alternative to liver biopsy for the quantitation of liver iron content. A systematic investigation of the influence of the region-of-interest size and placement has not been conducted. |
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