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大肠癌雌激素与孕激素受体检测的探讨
引用本文:孙荣超. 大肠癌雌激素与孕激素受体检测的探讨[J]. 肿瘤防治研究, 1996, 23(1): 32-33
作者姓名:孙荣超
作者单位:无锡市第一人民医院,214002
摘    要:
 本文应用E2-HRP、Pg-HRP亲合组化法对80例大肠癌切除标本进行了ER、PgR检测,结果大肠癌的ER、PgR阳性率分别为45.0%和36.3%,大肠癌ER、PgR阳性率与病人性别,肿瘤部位、大体类型,淋巴结转移无关。而绝经后的大肠癌患者,年龄越大,肿瘤分化程度越高,阳性率亦越高,提示ER、PgR水平高低可作为选择内分泌治疗和预测病人预后的参考指标。

关 键 词:大肠癌;雌激素受体;孕激素受体;亲和组化法

Assay of Estrogen and progesterone Receptor in large intestine cancer
Sun Rong Chao. Assay of Estrogen and progesterone Receptor in large intestine cancer[J]. Cancer Research on Prevention and Treatment, 1996, 23(1): 32-33
Authors:Sun Rong Chao
Affiliation:Department of pathology, WuXi 1st Hospital, WuXi
Abstract:
Eighty colo-rectal cancer tissues were assayed by using E2-HRP and Pg-HRP affinity histochemical method for contents of ER and PgR.The positiue rates of ER and PgR in Large intestine cancer were 45. 0% and 36. 3% respectively. There were no correlation between ER or PgR positivity and the sex of patient or location of tumor, metastasis of lymph nodes, type of tumor. The higher patients age and the better differentiation of cancer was the higher of the level of the ER and PgR contents would be.It is indicated that large intestine cancer may be an estrogen dependent tumor and endocrinotherapy might be of help.
Keywords:Carcinoma of large intestine  Estrogen receptor  progesterone receptor  Affinity histochemical method  
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