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Regulated cell death in cancer: from pathogenesis to treatment题录
作者姓名:Gong Linjing  Huang Dong  Shi Yujun  Liang Zong’an  Bu Hong
作者单位:1. Department of Respiratory and Critical Care Medicine;7. Institute of Clinical Pathology
基金项目:Natural Science Foundation of China(No. 82072689);
摘    要:Regulated cell death (RCD), including apoptosis, pyroptosis, necroptosis, and ferroptosis, is regulated by a series of evolutionarily conserved pathways, and is required for development and tissue homeostasis. Based on previous genetic and biochemical explorations of cell death subroutines, the characteristics of each are generally considered distinctive. However, recent in-depth studies noted the presence of crosstalk between the different forms of RCD; hence, the concept of PANoptosis appeared...

关 键 词:Anti-cancer therapy  Apoptosis  Cancer  Programmed cell death  Pyroptosis  PANoptosis  Necroptosis  Ferroptosis  Diagnosis
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