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Validation of a Circulating Tumor DNA-Based Next-Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing |
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| Authors: | Wael Al Zoughbi Jesse Fox Shaham Beg Eniko Papp Erika Hissong Kentaro Ohara Laurel Keefer Michael Sigouros Troy Kane Daniel Bockelman Donna Nichol Emily Patchell Rohan Bareja Aanavi Karandikar Hussein Alnajar Gustavo Cerqueira Violeta Beleva Guthrie Ellen Verner Jyothi Manohar Noah Greco David Wilkes Scott Tagawa Murtaza S. Malbari Kevin Holcomb Kenneth Wha Eng Manish Shah Nasser K. Altorki Andrea Sboner David Nanus Bishoy Faltas Cora N. Sternberg John Simmons Yariv Houvras Ana M. Molina Samuel Angiuoli Olivier Elemento Juan Miguel Mosquera |
| Affiliation: | 1. Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA;2. Personal Genome Diagnostics Inc., Baltimore, Maryland, USA;3. Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA;4. The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA;5. Institute for Computational Biomedicine, Weill Cornell Medicine, New York, New York, USA The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA;6. Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, New York, New York, USA The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA;7. Division of Thoracic Surgery, Weill Cornell Medicine, New York, New York, USA;8. Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, New York, USA The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA;9. Division of Thoracic Surgery, Weill Cornell Medicine, New York, New York, USA The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA;10. Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA Institute for Computational Biomedicine, Weill Cornell Medicine, New York, New York, USA The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA;11. Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, New York, New York, USA Department of Cell and Developmental Biology, Weill Cornell Medicine, New York, New York, USA The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA;12. Department of Surgery, Weill Cornell Medicine, New York, New York, USA The Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine and New York-Presbyterian, New York, New York, USA |
| Abstract: | |
| Keywords: | Circulating tumor DNA Microsatellite instability status Cancer immunotherapy |