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Randomized,Double-Blind,Placebo-Controlled Phase II Study of Yeast-Brachyury Vaccine (GI-6301) in Combination with Standard-of-Care Radiotherapy in Locally Advanced,Unresectable Chordoma |
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| Authors: | Peter Joseph DeMaria Marijo Bilusic Deric M. Park Christopher R. Heery Renee N. Donahue Ravi A. Madan Mohammad Hadi Bagheri Julius Strauss Victoria Shen Jennifer L. Marté Seth M. Steinberg Jeffrey Schlom Mark R. Gilbert James L. Gulley |
| Affiliation: | 1. Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA;2. Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA Contributed equally.;3. Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA University of Chicago, Chicago, Illinois, USA;4. Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA;5. Clinical Image Processing Service, National Institutes of Health, Bethesda, Maryland, USA;6. Biostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA;7. Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA |
| Abstract: | |
| Keywords: | Chordoma Immunotherapy Therapeutic vaccine Radiation therapy Randomized clinical trial |