苦参碱和氧化苦参碱对小鼠免疫功能的实验研究

[目的]探讨苦参碱和氧化苦参碱对免疫功能的作用。[方法]采用对T淋巴细胞酯酶染色率和溶血素抗体生成的方法。[结果]苦参碱和氧化苦参碱均可明显减少T淋巴细胞酯酶染色率;但可明显促进溶血素抗体形成。[结论]苦参碱和氧化苦参碱可明显降低T淋巴细胞功能,对体液免疫功能呈增强作用。

Experimental Study of Matrine and Oxymatrine on the Immune Function in Mouse

[Objective] To investigate effect of the matrine and oxymatrine on the immune function. [Methods] Esterase staining of T lymphocytes and antibody -producing hemolysin method. [Results] Matrine and oxymatrine T lymphocytes can be significantly reduced rate of esterase staining; but could significantly promote the formation of hemolysin antibody. [ Conclusion] Matrine and oxymatrine can significantly reduce T lymphocyte function, and humoral immune function was enhanced.