中药热熨配合金天格胶囊治疗早中期膝骨关节炎的临床研究

目的 观察中药热熨联合金天格胶囊治疗早中期膝骨关节炎的临床疗效。方法 将符合要求的70例膝关节炎患者随机分为2组，每组35例。治疗组，采用中药热熨配合口服金天格胶囊，对照组，口服盐酸氨基葡萄糖胶囊，连续3个月，分别于治疗前后对膝关节功能，静息疼痛进行临床评分，对比分析。结果 3个月后，两组患者治疗前后膝关节功能总体评分对比，均有非常显著性差异(P<0.01)，两组治疗均有效果；治疗后两组间膝关节功能总体评分对比，有非常显著性差异(P<0.01)，治疗组优于对照组,尤其是步行、上下楼功能的改善。治疗后两组间静息疼痛评分对比，有非常显著性差异(P<0.01)，治疗组优于对照组。结论 中药热熨配合金天格胶囊治疗早中期膝骨关节炎效果显著，具有很好的临床应用价值。

Clinical research of Chinese medicine hot ironing with Jintiange capsules in the treatment of early and middle stage of knee osteoarthritis

Objective To observe the effect of Chinese medicine hot ironing with Jintiange capsules in the treatment of early and middle stage of knee osteoarthritis. Methods Seventy knee osteoarthritis patients were randomly divided into 2 groups, with 35 cases in each group. Patients in the treatment group received Chinese medicine hot ironing with oral Jintiange capsules. Patients in the control group received oral glucosamine hydrochloride capsules. The treatment lasted for 3 months. The clinical scores of the knee joint function and rest pain before and after the treatment were analyzed. Results After 3 months, the total function scores in both group were higher than those before, and the difference was significant (P<0.01). The function scores between the two groups were significantly different (P<0.01). The effect in treatment group was better than that in control group, especially in the walk and up and down function. The rest pain scores after treatment were significantly different between the two groups (P<0.01). Conclusion The clinical effect of Chinese medicine hot ironing with Jintiange capsules in the treatment of early and middle stage of knee osteoarthritis is remarkable. The clinical application is of good value.