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游离皮片骨面埋置后骨-皮重附着的实验研究
引用本文:马戈,杨丹,赵晋龙,王瑞,刘彦普. 游离皮片骨面埋置后骨-皮重附着的实验研究[J]. 中国美容医学, 2011, 20(3): 438-442
作者姓名:马戈  杨丹  赵晋龙  王瑞  刘彦普
作者单位:1. 第四军医大学口腔医院颌面外科,陕西,西安,710032
2. 甘肃省临夏回族自治州68206部队卫生队,甘肃,临夏731100
3. 第四军医大学唐都医院医教部医疗科,陕西,西安,710038
摘    要:
目的:通过游离皮片骨面埋置植皮的实验研究,探索骨面埋置植皮的可行性;使移植皮肤和骨面间形成较为牢固的连接,满足种植床的软组织要求。方法:选择30只健康6月龄新西兰白兔(雌雄不限),随机分成A、B、C共3组,每组10只。分别在双侧下颌角处骨面埋置全厚、中厚皮片及滑行皮瓣覆盖双侧下颌角处骨面。实验组术后4周二期手术将移植皮片暴露,6周后处死所有动物,切取标本。进行大体标本观察,组织学观察(脱钙HE染色、MASSON染色)、透射电镜检查,进行统计学分析。结果:A组成活9例,B组成活17例,C组成活19例,χ2检验分AB、AC、BC三组两两比较成功率,AB两组及AC两组有统计学意义,BC两组无统计学意义。大体标本观察见成活皮肤色泽、质地好,与骨面结合紧密,成活皮肤无明显活动度;HE染色及MASSON三色法染色见皮肤层次分明,与骨面无间隙,皮肤内血管丰富;透射电镜下观察见真皮层与骨皮质结合紧密,未见间隙,真皮内胶原纤维部分穿入骨面,形成类似于骨膜附着的沙比纤维,提示皮肤-骨面连接紧密,且连接强度较高。结论:中厚皮片骨面埋置植皮是一种可行的方法。

关 键 词:颌骨缺损  生物封闭  游离皮瓣  自体骨移植  种植体

Experiment of new attchment between bone and skin after free skin flap on the bone
MA Ge,YANG Dan,ZHAO Jin-long,WANG Rui,LIU Yan-pu. Experiment of new attchment between bone and skin after free skin flap on the bone[J]. Chinese Journal of Aesthetic Medicine, 2011, 20(3): 438-442
Authors:MA Ge  YANG Dan  ZHAO Jin-long  WANG Rui  LIU Yan-pu
Affiliation:MA Ge1,YANG Dan2,ZHAO Jin-long1,WANG Rui3,LIU Yan-pu1(1.Department of Oral and Maxillofacial Surgery,School of Stomatology,The Fourth Military Medical University,Xi'an 710032,Shaanxi,China,2.Health Center of Military 68206,PLA,Linxia 731100,Gansu,3.Department of Health Service,Tangdu Hospital,China)
Abstract:
Objective By means of experimental study of free skin graft on the bone surface buried in the soft tissue,the feasibility of the method mentioned above is explored.Fairly firm connection between transplanted skin and bone surface is formed so that soft tissue meets the requirements of the implant site.Methods 30 healthy 6-month-old New Zealand white rabbits regardless of gender difference have been divided into 3 groups(A,B and C) randomly with 10 in each group.Full-thickness skin graft,split-thickness skin...
Keywords:jaw defect  biological seal  free skin flap  autograft  implant  
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