多层螺旋CT脑灌注成像与血管成像联合评价颈动脉狭窄与脑梗死的临床研究

目的 应用多层螺旋CT灌注成像与CTA联合评价颈内动脉狭窄与脑梗塞的相关性.资料与方法 59例急性脑梗死患者,在急性发作后6 h内行CT灌注成像和CTA检查.通过CTA对颈动脉狭窄程度进行评估,通过灌注图像评估脑梗塞的血流动力学状态.结果 梗死侧颈动脉血管狭窄发生率显著高于非梗死侧(P＝0.001),颈动脉狭窄程度与脑梗死所致神经功能缺损的严重程度之间明显相关(P<0.05).结论 联合CT灌注与CTA能评价颈内动脉狭窄程度与脑组织的血流灌注情况之间的关系.

Combination of Cerebral CT Perfusion and CT Angiography in the Evaluation of Acute Cerebral Infarction and Carotid Artery Stenosis

Objective To evaluate the correlation between carotid artery stenosis and acute cerebral infarction with the combination of cerebral CT perfusion and CT angiography. Materials and Methods CT perfusion and CTA were performed within 6 hours after onset of symptoms of ischemic stroke in 59 patients. CTA was employed to evaluate the degree of carotid artery stenosis, and CT perfusion was used to assess hemodynamic conditions of cerebral infarction. Results Incidence of ipsilateral carotid artery stenosis in the cerebral infarction was higher than that of contralateral carotid artery stenosis(P=0.001). There was significant correlation between the severity of carotid stenosis and neurologic impairment associated with ischemic stroke (P<0.05). Conclusion combination of cerebral CT perfusion and CT angiography could evaluate the relationship between the degree of carotid artery stenosis and perfusion of the brain tissue.