Tumorerkrankungen in der Schwangerschaft

The most frequent malignancy during pregnancy is cervical cancer, followed by Hodgkin’s lymphoma, breast cancer, and melanoma. Because of the older age of woman at pregnancy there has been an increase in the incidence. The diagnosis of a malignant tumor affects both the mother and her child; different therapy regimens have opposite effects on the prognosis of each one. The interdisciplinary dialogue with the mother attempts to find the optimal therapeutic modalities. Despite potentially negative effects of radiologic diagnostics, no time should be lost in finding the diagnosis. Gold standard methods are ultrasound and MRI. There is a lack of data regarding the different therapies. Surgery seems to be safe. Radiotherapy as well as endocrine therapy should not be done during pregnancy. Chemotherapy is regarded to be safe during the second and third trimesters, but it should not be applied earlier because of the teratogenic effects. Therapy with antibodies seems to be a promising treatment; long-term follow-up results are not available. In order to improve the knowledge about cancer in pregnancy, it is important to record case reports in http://www.germanbreastgroup.de/pregnancy.