| MCV、MCH在产前筛查地中海贫血中的应用价值 |
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| 引用本文： | 胡静云,陈善昌,赖万强,黄荣道,彭小媚,陈栋,粟福曌,龙丽娜. MCV、MCH在产前筛查地中海贫血中的应用价值[J]. 国际遗传学杂志, 2010, 33(2): 277-279,302. DOI: 10.3760/cma.j.issn.1673-4386.2010.05.005 |
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| 作者姓名： | 胡静云 陈善昌 赖万强 黄荣道 彭小媚 陈栋 粟福曌 龙丽娜 |
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| 作者单位： | 广西贺州市人民医院检验科,贺州,542800; |
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| 基金项目： | 贺州市科学研究与技术开发计划项目 |
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| 摘 要： | ![]()
Objective To explore the clinical value of mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH),hemoglobinA2(HbA2)'s result in hemoglobin electrophoresis joint detection in the prenatal diagnosis of Thalassemia. Methods MCV and MCH were detected by automatic blood cell analyzer,two hundred samples with MCV ＜ 80fl, MCH ＜ 26pg as experimental group and two hundred samples with MCV ＞ 80fl,MCH ＞ 26pg as control group were tested the HbA2 by hemoglobin electrophoresis. The correlation analysis was performed. To analysis the sensitivity and Specificity of the MCV and MCH as the screening method of the Thalassanemia. Results Of the 200 cases, 58.2% were detected for the Thalassanemia in the experimental group,2% were detected for the Thalassanemia in the control group. There were significant differences between the experimental group and the control group(t = 18. 214, P ＜ 0.01). Conclusion MCV and MCH could screen the Thalassanemia as effective index. Suggestted the suspects should do further examination for explicit diagnosis.
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| 关 键 词： | 地中海贫血 |
The value of MCV and MCH on screening thalassanemia in prenatal diagnosis |
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| HU Jing-yun,CHEN Shan-chang,LAI Wan-qiang,HUANG Rong-dao,PENG Xiao-mei,CHEN Dong,SU Fu-zhao,LONG Li-na. The value of MCV and MCH on screening thalassanemia in prenatal diagnosis[J]. International JOurnal of Genetics, 2010, 33(2): 277-279,302. DOI: 10.3760/cma.j.issn.1673-4386.2010.05.005 |
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| Authors: | HU Jing-yun CHEN Shan-chang LAI Wan-qiang HUANG Rong-dao PENG Xiao-mei CHEN Dong SU Fu-zhao LONG Li-na |
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| Abstract: | ![]()
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| Keywords: | MCVMCHMCVMCHThalassanemia |
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