两种药物治疗三叉神经痛的临床对比研究

目的:比较甲钴胺(弥可保)与卡马西平治疗原发性三叉神经痛的临床效果。方法:40例门诊确诊为原发性三叉神经痛的患者平分为两组,治疗组采用弥可保联合利多卡因治疗,对照组单独给予卡马西平治疗。结果:经过治疗后,治疗组有效率为90.0%.对照组有效率为70.0%,两组比较差异有统计学意义(P<0.05)。两组治疗期间均未发现血尿常规及肝肾功能改变,两组不良反应情况对比差异无显著意义,具有可比性(P>0.05)。结论:弥可保联合利多卡因治疗三叉神经痛能取得更好的治疗效果,且不增加不良反应,值得推广应用。

Comparison of the Effect of Two Drugs Regimen on Trigeminal Neuralgia

Objective:To compare the methylcobalamin treatment of primary trigeminal neuralgia with carbamazepine treatment. Methods:40 outpatients diagnosed with trigeminal neuralgia patients equally divided into two groups,treatment group were treated Methycobal Hdocaine,carbamazepine treatment given alone control group.Resulrs:After treatment.the treatment group was 90.0%.The control group was 70.0%,the difference was statistically significant(P<0.05).The two groups were not found in urine during treatment practices and changes in liver and kidney function,adverse reactions compared the two groups was no significant difference between comparable(P>0.05).Conclusion:Methycobal Hdocaine treatment of trigeminal neuralgia can achieve better treatment results,without increasing adverse effects,should be widely applied.