疏肝肺积方结合心理干预对原发性肺癌患者抑郁、焦虑的影响

背景与目的肺癌是我国最常见的恶性肿瘤之一,在治疗中给患者带来了巨大的躯体病痛和情绪障碍,本实验旨在研究疏肝肺积方结合心理干预对原发性肺癌患者抑郁情绪和焦虑情绪的影响,并进一步探讨患苦抑郁和焦虑之间的相互关系。方法将118例原发性非小细胞肺癌患者随机分为两组:疏肝肺积方结合心理干预加化疗组(联合治疗组57例)和单纯化疗组(61例)。联合治疗组采用疏肝肺积方和心理干预与化疗的联合应用;单纯化疗组仅接受化疗,共完成两次化疗,为一个总疗程。采用ZUNG抑郁自评量表和ZUNG焦虑自评量表测定心理状况。结果联合治疗组的抑郁、焦虑评分治疗后较治疗前下降(P<0.01);单纯化疗组的抑郁、焦虑评分治疗后较治疗前上升(P<0.01);联合治疗组的抑郁、焦虑评分比单纯化疗组患者明显下降(P<0.01);患者抑郁与焦虑指数呈正相关(P<0.01)。结论疏肝肺积方结合心理干预能缓解并改善肺癌患者的抑郁情绪和焦虑情绪,具有较好的临床疗效。

Study on the Effect of Feiji Decoction for Soothing the Liver Combined with Psychotherapy on the Quality of Life for Primary Lung Cancer Patients

Background and objective Lung cancer is the most common type among all malignant tumors,bringing huge pain and mood disorders to patients suffering from it.This study aims to evaluate the effect of the Feiji Decoction for soothing the liver combined with psychotherapy for depression and anxiety on patients with primary lung cancer.It also aims to further explore the relationship between depression and anxiety.Methods A total of 118 patients with primary non-small cell lung cancer were randomly divided into two groups.The combined therapy group consisted of 57 patients who were treated with Feiji Decoction for soothing the liver and psychotherapy combined with chemotherapy.The control group consisted of 61 patients who were treated with chemotherapy only.Both groups were observed for two treatment courses.The Zung Selfreported Depression Scales(SDS) and Zung Self-reported Anxiety Scales(SAS) were used to assess the patients’ psychology status in both groups before and after treatment scales.Results After treatment,the depression and anxiety scores of the therapy group remarkably decreased compared with scores before treatment,indicating a statistical significance(P<0.01).In comparison, after treatment,the depression and anxiety scores of the control group significanfly increased compared with scores before treatment,indicating a statistical significance(P<0.01) as well.The depression and anxiety scores of the therapy group significanfly decreased compared with scores of the control group,showing statistical significance(P<0.01).Thus,depression and anxiety score has a close co-relationship,showing significant positive correlation(P<0.01).Conclusion Feiji Decoction for soothing the liver combined with psychotherapy can alleviate depression and anxiety in patients with primary lung cancer. This therapy has good clinical therapeutic effect.