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Concurrent Langerhans cell histiocytosis and nephroblastoma
Authors:Ryoko Narui MD  Hiroshi Yagasaki MD  Yoshiyuki Takahashi MD  Asahito Hama MD  Nobuhiro Nishio MD  Hideki Muramatsu MD  Yoshie Shimoyama MD  Seiji Kojima MD
Affiliation:1. Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan;2. Department of Pathology and Clinical Laboratories, Nagoya University Hospital, Nagoya, Japan
Abstract:Both Langerhans cell histiocytosis (LCH) and nephroblastoma are rare in children. We report herein the first case of a patient with both diseases concurrently. A 2‐year‐old female presented with bone pain and swelling of the right humerus. As a result of the local incision biopsy, she was diagnosed as LCH. A nephroblastoma of the left kidney was discovered during her staging work‐up. After complete resection of the nephroblastoma, she received standard chemoradiotherapy for nephroblastoma. She is alive without relapse 14 months after initial presentation. Pediatr Blood Cancer 2009;52:662–664. © 2009 Wiley‐Liss, Inc.
Keywords:children  langerhans cell histiocytosis  nephroblastoma
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