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| 精子运动能力与一氧化氮关系的探讨 | |
| 引用本文： | 杨麦贵,同丽萍,张竹映,郑善銮,钟丽辉,皇海,徐焰,樊新,刘田. 精子运动能力与一氧化氮关系的探讨[J]. 中国优生与遗传杂志, 2004, 12(3): 110-111 |
| 作者姓名： | 杨麦贵 同丽萍 张竹映 郑善銮 钟丽辉 皇海 徐焰 樊新 刘田 |
| 作者单位： | 1. 第四军医大学西京医院检验科,西安,710032 2. 第四军医大学西京医院药剂科,西安,710032 3. 中国铁道建筑总公司西安医院 |
| 摘 要： | 目的探讨一氧化氮(NO)与精子运动能力的关系.方法采用镀铜镉还原荧光法,测定人精液中NO代谢产物硝酸盐(NO3-).参照WHO方法,在超高倍显微镜下观察精子存活率、活动力等. 结果 80例男性不育者其中15例NO浓度明显低于正常对照组精子活动力a b级<50%(P<0.01),以运动轨迹异常和头摆动幅度下降为主, 精子存活力>75%无明显差异(P>0.05);65例NO浓度显著高于正常对照精子活动力a b 级<50%,存活率<75% (P<0.001).结论 NO与精子运动功能有着密切关系.高浓度时明显抑制精子活动力及存活率.低浓度时精子存活率及功能有着维护作用,这对男性不育的病因研究和治疗有非常重要的临床价值. |
| 关 键 词： | 一氧化氮 男性不育 精子运动功能 |
| 文章编号： | 1006-9534(2004)03-0110-02 |
| 修稿时间： | 2003-07-10 |
Relationship between sperm movement and nitric oxide in sperm |
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| YANG Mai-gui ,TONG Li-ping ,ZHANG Zhu-ying ,ZHENG Shan-luan ,ZHONG Li-hui ,et al.. Relationship between sperm movement and nitric oxide in sperm[J]. Chinese Journal of Birth Health & Heredity, 2004, 12(3): 110-111 | |
| Authors: | YANG Mai-gui TONG Li-ping ZHANG Zhu-ying ZHENG Shan-luan ZHONG Li-hui et al. |
| Affiliation: | YANG Mai-gui 1,TONG Li-ping 2,ZHANG Zhu-ying 3,ZHENG Shan-luan 1,ZHONG Li-hui 1,et al. |
| Abstract: | Objective: To study the relationship between Sperm movement and nitric oxide in sperm. Methods: Fluorescence reducibility by copper-coated cadmium was used to detect nitrate from metabolism of nitric oxide in sperm. Results: In 80 sperm samples,there were 65 samples that concentration of nitric oxide is higher than hardly that in control group which activity grade a b is <50% and livability is <75% ( P <0.001). Conclusion: There was significant relationship between sterility and nitric oxide in sperm. |
| Keywords: | Nitric oxide Sterility in male Sperm movement |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |