我院769例药品不良反应报告分析

目的:了解我院药品不良反应(ADR)发生的特点及一般情况。方法:运用描述统计学的方法,对我院2011年收集到的769例ADR报告进行整理、分析。结果:在769例ADR报告中,年龄≤10岁和>50岁组其ADR构成比远高于其他组;抗微生物药是引起ADR的首要药物,有342例(44.47%);静脉给药是引起ADR的最主要给药途径,构成比高达64.50%;ADR临床表现最多的为皮肤及其附件损害,有235例(占30.56%)。结论:年龄、用药种类、给药途径三者可能均是ADR的影响因素;临床医师应充分考虑以上因素,降低ADR的发生率,提高临床合理用药水平。

Analysis of 769 Adverse Drug Reaction Reports in Our Hospital

OBJECTIVE： To investigate the characteristics and general information of adverse drug resection （ADR） in our hospital. METHODS： 769 ADR reports of our hospital in 2011 were summarized and analyzed by using descriptive statistics. RESULTS： Among 769 ADR reports, constituent ratio of ADR in below 10 years old and above 50 years old groups was greatly higher than other groups. 342 cases were caused by antimicrobial drugs （44.47%）. Intravenous injection was main routes of administration, accounting for 64.50%; most of clinical manifestations were lesion of skin and its appendants in 235 cases （30.56%）. CONCLUSION： Age, drug types, route of administration may be influencing factors of ADR. Clinician should consider above factors comprehensively to lower the incidence of ADR and to improve the level of rational drug use.