| 老年学习记忆减退大鼠齿状回突触的定量研究 |
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| 引用本文： | 洪岸 姚志彬. 老年学习记忆减退大鼠齿状回突触的定量研究[J]. 解剖学杂志, 1996, 19(3): 222-224 |
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| 作者姓名： | 洪岸 姚志彬 |
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| 作者单位： | 中山医科大学解剖学教研室!广州510089 |
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| 摘 要： | 据老年大鼠在Ｍｏｒｒｉｓ水迷宫中的行为表现，将其分为老年学习记忆减退和学习记忆正常两部分，采用透射电镜观察、拍片，对齿状回中分子层触的数量和大小进行体视学定量分析。
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| 关 键 词： | 学习记忆 齿状回 突触 老年 定量研究 |
QUANTITATIVE INVESTIGATION ON SYNAPSES OF DENTATE GYRUS IN AGED RATS DURING LEARNING AND MEMORY DECLINE |
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| Hong An,Yao Zhibin,Gu Yawning,Chen Yici,Kuang Guobi. QUANTITATIVE INVESTIGATION ON SYNAPSES OF DENTATE GYRUS IN AGED RATS DURING LEARNING AND MEMORY DECLINE[J]. Chinese Journal of Anatomy, 1996, 19(3): 222-224 |
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| Authors: | Hong An Yao Zhibin Gu Yawning Chen Yici Kuang Guobi |
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| Abstract: | Aged rats were divided into two groups according to their spatial memory capacity in the Morris water maze: aged rats with impaired memory and aged rats with normal memory. The number and the size of synapses in the middle molecular layer of the dentate gyrus were studied by quantitative stereology based on their TEM-graphies- Memory-impaired aged rats showed a significant decreases in numerical density and surface density of the synapses. but a significant increase in the average area of the single synaptic contact, as compared with young rats and aged rats with normal memory. These parameters were distinctly correlated with the rats' spatial memory capacity. |
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| Keywords: | senile learning and memory decline dentate gyurs synapse rat |
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