112例肝癌发病影响因素的病例对照研究

目的了解浙江省玉环县海岛居民肝癌的主要危险因素为肝癌的病因预防和人群防制提供依据。方法以2004-2005年发现的原发性肝癌患者112例（男99例,女13例,年龄57.5±13.2岁）进行1：2配比对病例对照研究,并用条件Logistic回归模型对所获资料进行单因素和多因素分析。结果多因素条件Logistic回归分析结果表明,父母恶性肿瘤史、乙型肝炎/HBsAg携带者、吃番茄、吃胡萝卜及吃腌制品的OR值分别为：6.03、246.48、4.02、0.05和5.70。结论乙型肝炎/HBsAg携带者、父母亲恶性肿瘤史者、吃腌制品（≥1次/周）、吃番茄可能是肝癌发生的危险因素;吃胡萝卜可能是肝癌发生的保护因素。

A Case-control Study on Influencing Factors of Liver Cancer with 112 Cases

Objective To investigate the main risk factors of liver cancer in the island residents of Yuhuan county and provide evidences for causes prevention and population prevention and control. Methods A 1 ： 2 matched case-control study was carried out with 112 cases of primary hepatic carcinoma （male： 99 cases; female： 13 cases; age： 57.5 ± 13.2 years） which were diagnosed from 2004 to 2005. The conditional logistic regression model was used for single factor analysis and multivariate analysis. Results The results of multivariate analysis showed the OR values of malignant tumor history, HBsAg infection, eating tomatoes, eating carrots and eating salted food were 6.03, 246.48, 4.02, 0.05 and 5.70 respectively. Conclusions The malignant tumor history, HBsAg infection, eating tomatoes and eating salted food （ t〉 1 time per week） may be risk facturs of liver cancer, eating carrots may be a protective factur.