| 骨形态生发蛋白6和铁超载骨质疏松关系的最新进展 |
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| 引用本文： | 贾鹏,徐又佳,钱忠明. 骨形态生发蛋白6和铁超载骨质疏松关系的最新进展[J]. 中华内分泌代谢杂志, 2011, 27(2). DOI: 10.3760/cma.j.issn.1000-6699.2011.02.027 |
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| 作者姓名： | 贾鹏 徐又佳 钱忠明 |
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| 作者单位： | 1. 苏州大学附属第二医院骨科,215004
2. 香港理工大学应用生物及化学科技学系铁代谢研究室 |
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| 基金项目： | 教育部博士学科基金,江苏省自然基金 |
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| 摘 要： | 近年来的研究发现体内铁超载能引起骨质疏松,骨形态生发蛋白6(BMP-6)能上调铁调素的表达.因此BMP-6可能在铁超载骨质疏松的恢复过程中起到一定的作用.本文就BMP-6与铁超载骨质疏松关系的最新文献进行综述,旨在为铁超载骨质疏松的进一步研究打下一定基础.Abstract：Recent researches have revealed that iron-overload could lead to osteoporosis and bone morphogenetic protein 6(BMP-6)could enhance the expression of hepcidin. Therefore, it is believed that BMP-6 might play a key role in the treatment of such kind of osteoporosis. This paper focuses on the newest papers regarding the relationship between BMP-6 and iron-overload osteoporosis in order to lay a foundation for further research on the osteoporosis induced by iron overloading.
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| 关 键 词： | 骨形态生发蛋白6 铁调素 铁超载 骨质疏松 |
Recent advances in the relationship between BMP-6 and iron-overload osteoporosis |
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| JIA Peng,XU You-jia,QIAN Zhong-ming. Recent advances in the relationship between BMP-6 and iron-overload osteoporosis[J]. Chinese Journal of Endocrinology and Metabolism, 2011, 27(2). DOI: 10.3760/cma.j.issn.1000-6699.2011.02.027 |
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| Authors: | JIA Peng XU You-jia QIAN Zhong-ming |
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| Abstract: | Recent researches have revealed that iron-overload could lead to osteoporosis and bone morphogenetic protein 6(BMP-6)could enhance the expression of hepcidin. Therefore, it is believed that BMP-6 might play a key role in the treatment of such kind of osteoporosis. This paper focuses on the newest papers regarding the relationship between BMP-6 and iron-overload osteoporosis in order to lay a foundation for further research on the osteoporosis induced by iron overloading. |
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| Keywords: | Bone morphogenetic proteins-6 Hepcidin Iron over-load Osteoporosis |
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