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Quality,Economics, and National Guidelines for Transcatheter Aortic Valve Replacement
Authors:Peter M. Pollak  Michael J. Mack  David R. Holmes Jr.
Affiliation:1. Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, MN;2. The Heart Hospital Baylor, Plano, TX
Abstract:
Transcatheter aortic valve replacement (TAVR) is a transformative technology for the treatment of aortic stenosis, requiring a multidisciplinary collaboration in the form of a “heart team” that includes interventional cardiologists and cardiac surgeons. As this new technology continues to disperse rapidly, its proper therapeutic role evolves and leads to important questions regarding who should perform the procedure, where it should be performed, and who should pay for it. Herein, we review the most recent guidelines governing the use of TAVR in the United States and Europe. We then summarize the available registry data, which, despite its limitations, presents the clearest picture of TAVR in clinical use. Finally, we discuss the costs and relative cost-effectiveness of TAVR. Taken together, these are the elements from which the larger questions surrounding TAVR must be answered.
Keywords:ACC, American College of Cardiology   AS, aortic stenosis   AUC, appropriate use criteria   AVR, aortic valve replacement   CMS, Center for Medicare Services   CV, cardiovascular   DRG, diagnostic-related group   ICER, incremental cost-effectiveness ratio   LOS, length of stay   LY, life-years   NCD, National Coverage Determination   PARTNER, Placement of Aortic Transcatheter Valve   PROM, predictive risk of mortality   QALY, quality-adjusted life-year   SAVR, surgical aortic valve replacement   STS, Society of Thoracic Surgery   TA, transapical   TAVR, transcatheter aortic valve replacement   TF, transfemoral   THV, transcatheter heart valve   SAVR, surgical aortic valve replacement   TVTR, Transcatheter Valve Therapy Registry   US, United States   VHD, valvular heart disease
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