| 哮喘模型大鼠气管的张开角及残余应变 |
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| 引用本文： | 王忆勤,李福凤,郭丽,李靖,张鹏,吴中华,燕海霞,石强,王惠芳,柳兆荣.哮喘模型大鼠气管的张开角及残余应变[J].中国生物医学工程学报,2006,25(1):88-91. |
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| 作者姓名： | 王忆勤 李福凤 郭丽 李靖 张鹏 吴中华 燕海霞 石强 王惠芳 柳兆荣 |
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| 作者单位： | 1. 上海中医药大学,上海,201203
2. 复旦大学生物力学实验室,上海,200433 |
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| 摘 要： | 对哮喘模型大鼠气管的无载荷状态和零应力状态进行分析。与正常组相比，模型大鼠气管软骨剪开的张开角及所对应的残余应变绝对值均较正常组显著增大（P〈0．05），而且随着x／L的增大而呈明显上升趋势。模型大鼠气管肌肉剪开的张开角及所对应的残余应变绝对值无显著变化，且沿气管轴向变化不明显。结果表明哮喘大鼠气管为了适应外在应力环境的变化，肌肉部分不断进行代偿性生长，导致哮喘大鼠气道重建。
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| 关 键 词： | 哮喘 大鼠气管 无载荷状态 零应力状态 张开角 残余应变 |
| 文章编号： | 0258-8021（2006）01-88-04 |
| 收稿时间： | 2003-01-10 |
| 修稿时间： | 2004-05-17 |
Opening Angles and Residual Strains in Asthma Rat Trachea |
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| WANG Yi-Qin,LI Fu-Feng,GUO Li,Li Jing,ZHANG Peng,WU Zhong-Hua,YAN Hai-Xia,SHI Qiang,WANG Hui-Fang,LIU Zhao-Rong.Opening Angles and Residual Strains in Asthma Rat Trachea[J].Chinese Journal of Biomedical Engineering,2006,25(1):88-91. |
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| Authors: | WANG Yi-Qin LI Fu-Feng GUO Li Li Jing ZHANG Peng WU Zhong-Hua YAN Hai-Xia SHI Qiang WANG Hui-Fang LIU Zhao-Rong |
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| Abstract: | In this study,the no-load state and zero-stress state of the asthma rat trachea were anlayazed. It was found that the opening angle and residual strains of the asthma rat trachea cut at the cartilaginous region was significantly larger than those of the normal rat. Compared with the coutrol rat, it was indicated that the opening angles and residual strains expressed by cutting at the muscular portion were basically identical along longitudinal location and those expressed by cutting at the cartilaginous region increased in the longitudinal direction in the asthma rta. The results shows that the muscle of trachea gradually growed because of changes of the mechanical environment, resulting in remodeling of the asthma rat trachea. |
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| Keywords: | asthma rat trachea zero-stress state no-load state opening angle residual strain |
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