| 不同频率重复经颅磁刺激对急性脑梗死患者静脉溶栓治疗的影响 |
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| 引用本文： | 顾正天,卢建新,张守成,郭学建,周威,徐蓉贞,徐珊珊. 不同频率重复经颅磁刺激对急性脑梗死患者静脉溶栓治疗的影响[J]. 临床神经病学杂志, 2011, 24(5) |
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| 作者姓名： | 顾正天 卢建新 张守成 郭学建 周威 徐蓉贞 徐珊珊 |
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| 作者单位： | 1. 211300,高淳县人民医院神经内科
2. 211300,高淳县人民医院影像科 |
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| 摘 要： | 目的比较不同频率的重复经颅磁刺激(rTMS)对急性脑梗死患者静脉溶栓治疗的影响。方法 141例急性脑梗死患者随机分为假rTMS治疗组、rTMS 1 Hz组、rTMS 2 Hz组、rTMS 5 Hz组、rTMS 10 Hz组和溶栓对照组,均予以尿激酶溶栓治疗。rTMS 1~10 Hz各组依次分别在溶栓同时给予rTMS 1 Hz、2 Hz、5 Hz、10 Hz治疗,假rTMS治疗组予以假rTMS刺激。所有患者于治疗前及治疗后24 h时进行美国国立卫生研究院卒中量表(NIHSS)评分,观察并记录各组不良反应情况。结果各组治疗后NIHSS评分均较治疗前明显下降(均P<0.05)。治疗后rTMS 1~10 Hz各组NIHSS评分均较溶栓对照组明显下降,其中rTMS 5 Hz组NIHSS评分最低(均P<0.05)。rTMS 1~10 Hz各组有效率(64.0%、76.2%、81.8%、83.3%)均明显高于假rTMS治疗组(42.3%)和溶栓对照组(47.8%)(均P<0.05)。其中,rTMS 2 Hz组、rTMS 5 Hz组与rTMS 10 Hz组有效率均高于rTMS 1 Hz组(均P<0.05)。各组间不良反应的比...
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| 关 键 词： | 脑梗死 溶栓 重复经颅磁刺激 疗效 |
Influence of repetitive transcranial magnetic stimulation with different frequencies on intravenous thrombolytic therapy in patients with acute cerebral infarction |
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| GU Zheng-tian,LU Jian-xin,ZHANG Shou-cheng,et al.. Influence of repetitive transcranial magnetic stimulation with different frequencies on intravenous thrombolytic therapy in patients with acute cerebral infarction[J]. Journal of Clinical Neurology, 2011, 24(5) |
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| Authors: | GU Zheng-tian LU Jian-xin ZHANG Shou-cheng et al. |
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| Affiliation: | GU Zheng-tian,LU Jian-xin,ZHANG Shou-cheng,et al.Department of Neurology,Gaochun People's Hospital,Gaochun 211300,China |
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| Abstract: | Objective To compare the influence of repetitive transcranial magnetic stimulation(rTMS) with different frequencies on intravenous thrombolytic therapy in patients with acute cerebral infarction.Methods One hundred and fourty-one patients with acute cerebral infarction were randomly divided into sham rTMS group,rTMS 1 Hz group,rTMS 2 Hz group,rTMS 5 Hz group,rTMS 10 Hz group and thrombolytic control group.All of them were accepted thrombolytic therapy by urokinase.At the same time of thrombolytic therapy,th... |
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| Keywords: | cerebral infarction thrombolysis repetitive transcranial magnetic stimulation curative effects |
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