| 海洋真菌Aspergillus versicolor菌丝体中化学成分的研究 |
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| 引用本文： | 张海龙,田黎,华会明,裴月湖.海洋真菌Aspergillus versicolor菌丝体中化学成分的研究[J].中国海洋药物,2004,23(5):14-17. |
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| 作者姓名： | 张海龙 田黎 华会明 裴月湖 |
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| 作者单位： | 1. 沈阳药科大学中药学院,辽宁,沈阳,110016
2. 国家海洋局第一海洋研究所,山东,青岛,266003 |
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| 基金项目： | 国家 8 6 3项目 (2 0 0 1AA6 2 4 0 2 0 ) |
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| 摘 要： | 自海洋真菌Aspergillus versicolor菌丝体的丙酮和甲醇萃取部分进行化学成分的研究，从中分离得到7个化合物．经光谱数据分析．鉴定其结构为柄曲菌素(Ⅰ)、6-甲氧基柄曲菌素(Ⅱ)、奥佛尼红素(Ⅲ)、酪氨酸(Ⅳ)、3-甲基-吡咯并哌嗪2，5-二酮(Ⅴ)、3-异丙基-吡咯并哌嗪2．5-二酮(Ⅵ)和尿素(Ⅶ)。其中化合物Ⅳ．Ⅴ和Ⅵ为首次从该属菌中分离得到。
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| 关 键 词： | 柄曲菌素 化学成分 首次 酪氨酸 分离 海洋真菌 红素 哌嗪 二酮 甲基 |
| 文章编号： | 1002-3461(2004)05-0014-04 |
Studies on the chemical constituents from the mycelia of marine fungus Aspergillus versicolor |
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| ZHANG Hai-long,TIAN Li,HUA Hui-ming,PEI Yue-hu.Studies on the chemical constituents from the mycelia of marine fungus Aspergillus versicolor[J].Chinese Journal of Marine Drugs,2004,23(5):14-17. |
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| Authors: | ZHANG Hai-long TIAN Li HUA Hui-ming PEI Yue-hu |
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| Institution: | ZHANG Hai-long 1,TIAN Li 2,HUA Hui-ming 1,PEI Yue-hu 1 |
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| Abstract: | Objective To study the chemical constituents from mycelium of marine fungus Aspergillus versicolor.Methods The compounds were separated by column chromatography and their structures were elucidated based on chemical and spectral analysis. Results Seven compounds have been isolated from the acetone and methanol extracts from the mycelia of Aspergillus versicolor. Their structures were determined as sterigmatocystin (I), 6-methoxysterigmatocystin (II), averufin (III), tyrosine (IV), 3-methyl-pyrrolopiperazine-2, 5-dione (V), 3-isopropyl-pyrrolopiperazine-2, 5-dione (VI), carbamide (VII). Conclusion Compounds IV,V and VI were isolated for the first time from this genus of marine fungi. |
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| Keywords: | marine fungus mycelium sterigmatocystin Aspergillus versicolor |
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