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| 苯妥英钠对大鼠实验性胃溃疡的保护作用 | |
| 引用本文： | 王传功,林丽文,辛勤,刘善庭. 苯妥英钠对大鼠实验性胃溃疡的保护作用[J]. 济宁医学院学报, 2005, 28(3): 16-17 |
| 作者姓名： | 王传功 林丽文 辛勤 刘善庭 |
| 作者单位： | 济宁医学院药理学教研室;济宁医学院药理学教研室;济宁医学院药理学教研室;济宁医学院药理学教研室 |
| 摘 要： | 目的观察苯妥英钠对大鼠实验性胃溃疡的保护作用。方法采用水束缚应激法、大鼠冰醋酸烧灼法两种溃疡模型。结果苯妥英钠高、低剂量组均显示出保护作用（P〈0．05），但高剂量组的保护作用不如低剂量组的明显。结论苯妥英钠对大鼠实验性胃溃疡的胃粘膜有一定的保护作用，且保护作用与剂量成负相关性，低剂量的保护作用要好于高荆量。 |
| 关 键 词： | 苯妥英钠 胃溃疡 保护 |
| 收稿时间： | 2005-08-22 |
| 修稿时间： | 2005-08-22 |
PROTECTIVE EFFECT OF PHENYOIN SODIUM(PHT) ON EXPERIMENTAL GASTRIC ULCER IN RATS |
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| Wang Chuangong , Lin Liwen , Xin Qin , et al. PROTECTIVE EFFECT OF PHENYOIN SODIUM(PHT) ON EXPERIMENTAL GASTRIC ULCER IN RATS[J]. Jounal of Jinning Medical College, 2005, 28(3): 16-17 | |
| Authors: | Wang Chuangong Lin Liwen Xin Qin et al |
| Affiliation: | Department of pharmacology,Jining medical college |
| Abstract: | Objective To observe the protective effect of PHT on experimental gastric ulcer.Methods Experimental rat gastric ulcer models including water logging stress-restraint ulcer, and acetic acid impaired gastric ulcer in rat.Results PHT showed protective effect in both high and low dose groups(P<0.05),but low dose group showed better protective effect than high dose group.Conclusion PHT showed protective effect on experimental rat gastric ulcer,and the proteceive effect is pure with higher dose. |
| Keywords: | Phenytoin Gastric ulcer Protective effect |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |