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Rhabdoid meningioma presenting with subependymal and diffuse meningeal involvement but no mass lesion
Authors:Kate E. Ahmad  Suad Al-Jahdhami  Omar Ahmad
Affiliation:1. Institute of Pathology, University of Bern, 3010 Bern, Switzerland;2. Department of Neurosurgery, Inselspital, Bern University Hospital, and University of Bern, 3010 Bern, Switzerland;3. Department of Neuroradiology, Inselspital, Bern University Hospital, and University of Bern, 3010 Bern, Switzerland;4. Institute of Pathology “Laenggasse”, 3012 Bern, Switzerland
Abstract:Rhabdoid meningiomas are rare, aggressive tumours of the meninges that have a generally poor prognosis. We report a 49-year-old man with a background history of sarcoidosis who presented with nausea and vomiting. Imaging showed generalised leptomeningeal and subependymal enhancement suggestive of chronic meningitis. He had multiple lumbar punctures and a brain biopsy, none of which led to a pathological diagnosis. He died within months, and a postmortem examination was performed. At this stage, a diagnosis of rhabdoid meningioma was made. The clinical and radiological presentation of rhabdoid meningioma as a diffuse leptomeningeal process without a mass lesion is unique. All other published cases of rhabdoid meningioma have been of a discrete lesion. This highlights the importance of a tissue diagnosis in patients where the imaging is non-specific. A brief review of rhabdoid meningioma follows.
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