TACE联合^131I—碘化油内放射治疗原发性肝细胞癌疗效观察

目的 探讨原发性肝细胞癌肝动脉栓塞化疗（ＴＡＣＥ）联合 ＾１３１Ｉ－碘化油内放射治疗的疗效。方法 原发性肝细胞癌６８例，随机分为２组进行治疗。Ａ组（ＴＡＣＥ组）：经导管肝动脉栓塞化疗，３４例；Ｂ组（联合治疗组）；肝动脉栓塞化疗联合＾１３１Ｉ－碘化油内放射治疗，３４例。结果 ＴＡＣＥ组二期手术切除率８．８％，组织学检查切除病灶的完全坏死率为０，患者１、２、３年生存率分别为６４．３％、３９．３％和２１

Transcatheter Arterial Chemo Embolization Combined with ~(131)I Lipiodol for the Treatment of Primary Hepatocellular Carcinoma

Objective To study the therapeutic effect of transcatheter arterial chemoembolization(TACE) combined with iodine 131 Lipiodol( 131 I Lipiodol) for primary hepatocellular carcinoma(PHC).Methods 68 patients with PHC were divided into two groups.In group A,34 patients were treated by TACE,and in group B,34 patients treated by TACE combined with 131 I Lipiodol.Results In group A, second stage surgical resection rate was 8.8%,histologic examination of cancer specimens obtained from hepatectomy showed that TACE could not cause complete necrosis.The 1 ,2 ,and 3 year survival rate of the treated cases was 64.3%, 39.3% and 21.4%,respectively.In contrast,in group B,the second stage surgical resection rate was 29.4%,combination therapy resulted in complete histologic necrosis in 76.9% of patients.The 1 ,2 ,and 3 year survival rate was 96.4%,82.1% and 60.7%,respectively.Conclusion The therapeutic effect of TACE combined with 131 I Lipiodol is much better than that of TACE alone.