戈壁天冬中的木脂素和酚酸类化学成分

目的 研究天门冬属植物戈壁天冬中的化学成分。方法 使用硅胶柱色谱、凝胶柱色谱、制备液相色谱及薄层色谱等多种色谱分离技术对戈壁天冬全草95%乙醇提取物进行分离纯化，利用理化常数和多种波谱技术对化合物进行了结构鉴定。结果 从戈壁天冬中分离鉴定了9个化合物，其中6个是木脂素类化合物，分别为(+)-松脂素（1），(-)-丁香脂素（2），(+)-丁香脂素-4'-O-β-D-葡萄糖苷（3），(-)-表丁香脂素（4），(+)-nyasol（5），(+)-4'-O-methylnyasol（6）；3个酚酸类化合物，分别为阿魏酸（7），异阿魏酸（8），咖啡酸（9）。结论 所有化合物均为首次从本植物中分离得到，其中化合物1~4和8为首次从天门冬属植物中分离得到。 

Lignans and Phenolic Compounds from Asparagus Gobicus

OBJECTIVE To study the chemical constituents of Asparagus Gobicus. METHODS Whole herb of Asparagus gobicus were extracted with 95% alcohol. Repeated silica gel column chromatography，Sephadex LH-20 chromatography， preparative HPLC and thin layer chromatography were applied for chemical constituents isolation and purification. Chemical structures of the compounds were elucidated by physical properties and spectra analysis such as NMR and ESI-MS. RESULTS Nine compounds were isolated from the extract of Asparagus gobicus. Six compounds were identified as lignans: (+)-pinoresinol（1）， (-)-syringaresinol（2）， (+)-syringaresinol-4'-O-β-D-glucopyranoside（3）， (-)-episyringaresinol（4）， (+)-nyasol（5）， (+)-4'-O-methylnyasol（6）. Three compounds were phenolic compounds: ferulic acid（7）， isoferulic acid（8）， caffeic acid（9）. CONCLUSION All compounds were isolated for the first time from this plant，and compounds 1~4 and 8 were obtained from the genus Asparagus for the first time.