| 微柱凝胶技术在新生儿溶血病检测中的应用 |
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| 引用本文： | 黎世杰,罗广平,赵阳. 微柱凝胶技术在新生儿溶血病检测中的应用[J]. 热带医学杂志, 2006, 6(5): 549-551 |
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| 作者姓名： | 黎世杰 罗广平 赵阳 |
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| 作者单位： | 广州血液中心,广州,510095;广州血液中心,广州,510095;广州血液中心,广州,510095 |
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| 摘 要： | 目的建立微柱凝胶技术在新生儿溶血病(HDN)血清学检查的方法。方法采用微柱凝胶抗人球蛋白方法和传统抗人球蛋白试验检测HDN标本,通过比较,进行两种方法学评价。结果2004年送检标本中共检出430例HDN,其中ABO-HDN416例,RH-HDN13例,MN-HDN1例,两种方法HDN实验阳性率无显著性差异。在直抗试验中微柱凝胶法阳性率65.38%,抗人球法阳性率58.17%,结果有差异("2=4.518,0.025
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| 关 键 词： | 微柱凝胶技术 新生儿溶血病 抗人球蛋白试验 |
| 文章编号： | 1672-3619（2006）05-0549-03 |
| 收稿时间： | 2005-11-07 |
| 修稿时间： | 2006-01-21 |
Application of Micro-Column Gel Technique in Serological Study of Hemolytic Disease of Newborn |
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| LI Shi-jie,LUO Guang-ping,ZHAO Yang. Application of Micro-Column Gel Technique in Serological Study of Hemolytic Disease of Newborn[J]. Journal Of Tropical Medicine, 2006, 6(5): 549-551 |
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| Authors: | LI Shi-jie LUO Guang-ping ZHAO Yang |
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| Abstract: | Objective To examine the applicability of micro-column gel technique in serological study of hemolytic disease of newborn(HDN).Methods The results of the micro-column gel coombs test(MGCT)were compared with the results of the conventional tube test(CTT).Results Of 430 cases of HDN in 2004,416 cases were ABO-HDN,13 cases were RH-HDN,and 1 case was MN-HDN.Significant difference between MGCT and CTT was not seen.In DAT test,272 cases were found to be positive with MGCT(positive rate was 65.38%),while 242 cases were found to be positive with CTT(positive rate was 58.17%).The result obtained from CTT was significantly different from MGCT(x2=4.518,0.025
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| Keywords: | microcolumn gel technique hemolytic disease of newborn direct antiglobulin test |
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