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IL-2、IL-6表达与ds-DNA在SLE检测中的相关性和临床意义
引用本文:张运丽,朱燕,高戈. IL-2、IL-6表达与ds-DNA在SLE检测中的相关性和临床意义[J]. 现代医药卫生, 2007, 23(4): 477-478
作者姓名:张运丽  朱燕  高戈
作者单位:1. 中南大学湘雅医院检验科,湖南,长沙,410008
2. 中南大学湘雅医学院检验系,湖南,长沙,410013
摘    要:
目的:探讨系统性红斑狼疮(SLE)患者血清中IL-2、IL-6的表达与ds-DNA的关系。方法:用酶联免疫吸附试验(ELISA)检测40例SLE患者血清中IL-2、IL-6和抗ds-DNA抗体水平。结果:SLE患者血清IL-2水平较正常组明显降低(P<0.01),而血清中IL-6水平较正常组增高(P<0.05)。结论:在SLE患者血清中IL-6水平与ds-DNA呈正相关,对于SLE的诊断和疗效观察有重要的临床意义。

关 键 词:SLE  IL-2  IL-6  ds-DNA
文章编号:1009-5519(2007)04-0477-02
修稿时间:2006-09-21

Correlation and clinical value between IL-2,IL-6 and ds-DNA in the serum of SLE patients
ZHANG Yun-li,ZHU Yan,GAO Ge. Correlation and clinical value between IL-2,IL-6 and ds-DNA in the serum of SLE patients[J]. JOURNAL OF MODERN MEDICINE & HEALTH, 2007, 23(4): 477-478
Authors:ZHANG Yun-li  ZHU Yan  GAO Ge
Affiliation:1.Clinical Laboratory, Xiangya Hospital, Central South University, Changsha 410008,Chian;2.Xiangya School of Medicine,Central South University, Changsha 410013,China
Abstract:
Objective:To investigate the correlation between IL-2,IL-6 and anti-double-stranded DNA antibodies in the serum from the patients with SLE.Methods:Applying ELISA technique to analyse the IL-2,IL-6 and anti-dsDNA in the serum from 40 SLE patients.Results:The level of serum IL-2 was lower than that of control group.The level of IL-6 was higher than that of control group.Conclusion:There is positive correlation between IL-6 and anti-dsDNA in the serum from 40 SLE patients,that is important to diagnosis and treatment of SLE.
Keywords:SLE  IL-2  IL-6  ds-DNA
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